ISSN: 2375-3005
American Journal of Microbiology and Biotechnology  
Manuscript Information
 
 
Spectroscopic and Antimicrobial Activities of Biologically Active Agent Derived from Neem (Azadirechta indica) Oil
American Journal of Microbiology and Biotechnology
Vol.6 , No. 1, Publication Date: Nov. 28, 2019, Page: 1-8
1295 Views Since November 28, 2019, 268 Downloads Since Nov. 28, 2019
 
 
Authors
 
[1]    

Priyanka Kumawat, Department of Chemistry, Samrat Prithviraj Chouhan Government College, Ajmer, India.

[2]    

Rashmi Sharma, Department of Chemistry, Samrat Prithviraj Chouhan Government College, Ajmer, India.

[3]    

Nitin Sharma, Department of Biochemistry, Dr. Sampurnanand Medical College, Jodhpur, India.

 
Abstract
 

In this study, we evaluated the antimicrobial potency of copper (II) soap and copper soap complex synthesized / formulated in our laboratory. The solid copper (II) soap derived from Neem (Azadirachta indica) oil and its complex with ligand containing nitrogen and sulphur atoms thiourea has been synthesized and characterized by elemental analysis, IR spectroscopy and biological studies. Elemental analysis was done for soap and complex for their metal content following standard procedures. The complex under study was prepared in two steps. In the first step, copper soap was prepared and in the second step complexation of copper soap was done with ligand thiourea. The absorption bands were found corresponding to the absorption bands of pure copper neem soap. Apart from these absorption bands the bands were also observed corresponding to the ligand moiety. In this study ESR Spectra, NMR Spectra, IR Spectra and Antimicrobial Activities against five bacteria related with skin disease have been done. Neem (Azadirechta indica) oil is widely used as insecticides, lubricant, drugs for variety of diseases. The synthesized biocidal molecule from neem oil and copper metal has been confirmed by spectroscopic studies. The antimicrobial studies and findings have high medical, industrial and economic significance as copper (II) soap and copper (II) soap complex could be hamessed in the formulation of medicated soaps and other externally applicable ointments and pharmaceuticals related with skin disease.


Keywords
 

Copper (II) Soap, Complex, Spectroscopic, Biological Studies


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