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Vol.4 , No. 6, Publication Date: Nov. 14, 2017, Page: 100-107
&description=In this study, we evaluated the antimicrobial properties of phenolic extracts of the fruit of <i>Punica granatum</i> on microbial strains associated with several human pathologies. The extracts also underwent a phytochemical study. The evaluation of the antimicrobial properties was carried out by the agar diffusion method for the determination of the diameters of the zones of inhibition and by the micro dilution method in liquid medium for the determination of the minimum inhibitory concentrations MIC and MBC. At the end of the antimicrobial tests, we found that this extract has a very high activity with diameters of zones of inhibition varying between 07 and 22 mm. However, regardless of the germ, methanol extract was found to be the most active with Inhibitory Minimum Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values of 0.03 and 0.07 mg/ml. According to our results, the antimicrobial activity of the phenolic extracts of <i>Punica granatum</i> highlighted in this study may justify the therapeutic use of this plant in traditional medicine in the treatment of a large number of microbial infections.&picture=http://www.aascit.org/aascit/decorators/img/journal/919.jpg)
| [1] | Athmen Reguieg Yssaad, Laboratory of Pharmacogonosy Api Phytotherapy, University Abdelhamid Ibn Badis of Mostaganem, Algeria. |
| [2] | Kheira Hammadi, Laboratory of Pharmacogonosy Api Phytotherapy, University Abdelhamid Ibn Badis of Mostaganem, Algeria. |
In this study, we evaluated the antimicrobial properties of phenolic extracts of the fruit of Punica granatum on microbial strains associated with several human pathologies. The extracts also underwent a phytochemical study. The evaluation of the antimicrobial properties was carried out by the agar diffusion method for the determination of the diameters of the zones of inhibition and by the micro dilution method in liquid medium for the determination of the minimum inhibitory concentrations MIC and MBC. At the end of the antimicrobial tests, we found that this extract has a very high activity with diameters of zones of inhibition varying between 07 and 22 mm. However, regardless of the germ, methanol extract was found to be the most active with Inhibitory Minimum Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values of 0.03 and 0.07 mg/ml. According to our results, the antimicrobial activity of the phenolic extracts of Punica granatum highlighted in this study may justify the therapeutic use of this plant in traditional medicine in the treatment of a large number of microbial infections.
Keywords
Punica granatum, Phytochemical Analysis, Antibacterial Activity, Phenolic Extracts
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