Indexing
All Issues
Submission
Author Guidelines
Reviewers
Editorial Members
Publication Fee
Vol.5 , No. 1, Publication Date: Feb. 1, 2018, Page: 29-34
 were bought from the Animal house of the National Veterinary Research Institute, Vom, Jos. They were randomly assigned to five groups (n=5). They were meticulously allowed to acclimatize for one month. Red Wine (12%), White wine (12%), Rose wine (12%), ethanol (12%) and distilled water (control) were administered orally to groups 1, 2, 3, 4 and 5 respectively for 14 days. The administration was done in accordance with Pedro Montilla’s method, 2005 (400ml/70kg body weight, with 12hr- light/dark cycle). The rats were later sacrificed and subjected to biochemical and histological analysis. Rose wine emerged the best in significantly reducing (P<0.05) LDL-cholesterol. The rats administered red wine and white wine behaved identically, both wines had adverse effects on liver function and Liver histology but they pose no damage on the lipid profile. Moreover, red wine and white wine showed good antibacterial activity and preserved heart’s histological state. All the wines are good for the heart. However, red wine is better than the other table wines. It has the highest content of resveratrol.&picture=http://www.aascit.org/aascit/decorators/img/journal/908.jpg)
| [1] | Kukoyi Ayobami Jahdahunsi, Department of Biochemistry, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria. |
| [2] | Arowora Kayode Adebisi, Department of Biochemistry, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria. |
| [3] | Adegbite Oluwatobi Samuel, Department of Biochemistry, Osun State University, Osogbo, Nigeria. |
| [4] | Akinsanya Yetunde Ifeoma, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria. |
| [5] | Ciroma Ishaku James, Department of Biochemistry, Faculty of Pure and Applied Sciences, Federal University, Wukari, Nigeria. |
This research was designed to determine the effect of table wines on the heart and Liver. Six weeks old, twenty-five wistar rats (weighing 191 ± 9.4g) were bought from the Animal house of the National Veterinary Research Institute, Vom, Jos. They were randomly assigned to five groups (n=5). They were meticulously allowed to acclimatize for one month. Red Wine (12%), White wine (12%), Rose wine (12%), ethanol (12%) and distilled water (control) were administered orally to groups 1, 2, 3, 4 and 5 respectively for 14 days. The administration was done in accordance with Pedro Montilla’s method, 2005 (400ml/70kg body weight, with 12hr- light/dark cycle). The rats were later sacrificed and subjected to biochemical and histological analysis. Rose wine emerged the best in significantly reducing (P<0.05) LDL-cholesterol. The rats administered red wine and white wine behaved identically, both wines had adverse effects on liver function and Liver histology but they pose no damage on the lipid profile. Moreover, red wine and white wine showed good antibacterial activity and preserved heart’s histological state. All the wines are good for the heart. However, red wine is better than the other table wines. It has the highest content of resveratrol.
Keywords
Antioxidant, Heart, Lipid Profile, Liver, Table Wine, LDL Cholesterol
Reference
| [01] | McGovern, P., Glusker, D., Exner, L. Neolithic resinated wine. Nature 1996; 381, 480-481. |
| [02] | McDonald, J. Nutrition, A Symposium on Wine, Health and Society Wine Institute, Washington. D. C. 1986. |
| [03] | Renaud S. Wine, Alcohol, Platelets and the French Paradox for Coronary Heart Disease. The Lancet, 1992; 339: 1523-1526. |
| [04] | Ahsan, R., Islam, M., Bulbul, J. I., Musaddik, A., Haque, E. Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride-induced hepatotoxicity in rats Eur J Sci Res, 2009; 37 (2): 302-310. |
| [05] | Subramaniam, S., Khan, H. B. H., Elumalai, N., Lakshmi, S., Y., S.. Hepatoprotective effect of ethanolic extract of whole plant of Andrographis paniculata against CCl4-induced hepatotoxicity in rats Comp Clin Path, 2015; (24): 1-7. |
| [06] | Alrawi, R., Alrawi, R. Conventional Concepts in Coronary HeartDisease and New Thoughts in its Prediction. Insights Med Phys. 2017; Vol. 2 No. 2: 5. |
| [07] | Pedro, M., Isabel, E., Maria C., Muñoz, I., B., Juan, R., Muñoz-Castañeda, I., T., Protective effect of red wine on oxidative stress and antioxidant enzyme activities in the brain and kidney induced by feeding high cholesterol in rats. Clinical Nutrition 2006; 1, 146-153. |
| [08] | Geetha, D., K.,. Practical Biochemistry. Jaypee Brothers Medical Publishers (P) Ltd, UK. 2011. |
| [09] | Avwioro, O., G. Staining reactions of microwave processed tissues compared with conventional paraffin wax processed tissues. European Journal of Experimental Biology; 2011; 1 (1): 57-62. |
| [10] | Choji, T., P., P., Ngokere, A., A., Ogenyi, S., I., Kumbish, P., R. Histo-architechtural Evaluation of Conventional Versus Two Rapid Microwave Processing Techniques. British Biotechnology Journal 2015; 8 (3): 1-19. |
| [11] | Vashist, H., Sharma, D., Gupta, A. Different models to evaluate antimicrobial agents-A review. innovare journal of life science, 2013; 1 (2): 1-6. |
| [12] | Valgas, C., de Souza, S., M., Smania, E., F., A., Smania, Jr., A Screening methods to determine antibacterial activity of natural products. Brazilian Journal of Microbiology,.2002; 38: 369-380. |
| [13] | Hannes, H. Alcohol Consumption in Concomitant Liver Disease: How Much is Too Much? Curr Hepatology Rep 2017; 16: 152-157. |
| [14] | Giuseppe, L., Massimo, F., Gian, C., G. Red wine and cardiovascular health: the “French Paradox” revisited International Journal of Wine Research 2010; 2: 1-7. |
| [15] | KLATSKY, A., L., Cardiovascular effects of alcohol. Scientific American Science and Medicine 1995; 2 (2): 28-37. |
| [16] | Benjamin, C., Ugbogu, O., C.. Measurement and dilutions. In-Onyeagba, A. (Ed.): laboratory guide for microbiology. Imo state, Nigeria: crystal Publisher. 2004. |
| [17] | Zhao, W., Zhang, L., Xu, Y., Zhang, Z., Ren, G., Tang, K. Hepatic stellate cells promote tumor progression by enhancement of immunosuppressive cells in an orthotopic liver tumor mouse model. Lab Invest. 2014; 94: 182-191. |
| [18] | Ranjna, C.. Practical clinical biochemistry methods and interpretation. Textbook of practical. 2000; 152-170. |
