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International Journal of Clinical Medicine Research

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Preliminary Screening of Risk Factors of Female Infertility at Hyderabad City of Sindh, Pakistan

International Journal of Clinical Medicine Research
Vol.7 , No. 1, Publication Date: Jan. 10, 2020, Page: 1-5

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Authors

[1]	Muzna Paras, Institute of Biochemistry, Faculty of Natural Sciences, University of Sindh, Jamshoro, Pakistan.
[2]	Naseem Aslam Channa, Institute of Biochemistry, Faculty of Natural Sciences, University of Sindh, Jamshoro, Pakistan.
[3]	Safdar Ali Amur, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
[4]	Quratulain Khuhro, Institute of Biochemistry, Faculty of Natural Sciences, University of Sindh, Jamshoro, Pakistan.
[5]	Najaf Ali Soomro, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
[6]	Muhammad Haneef Mugheri, Institute of Biochemistry, Faculty of Natural Sciences, University of Sindh, Jamshoro, Pakistan.
[7]	Amna Yasin Awan, Institute of Biochemistry, Faculty of Natural Sciences, University of Sindh, Jamshoro, Pakistan.

Abstract

This study was aimed to explore the epidemiological factors associated with female infertility at Hyderabad Sindh, Pakistan. To achieve the aim, a total of 60 infertile females and 47 healthy females who served as controls were selected. A standard questionnaire was applied by interviewing methods at the Australian Concept and Fertility Center Hyderabad. The participants were verbally informed regarding the procedure and aim of the study. All of them were asked about their personal lifestyle, medical history, infertility and menstruation history. Primary data was compiled by SPSS and a chi-squared test with 95% confidential interval was applied to calculate odds ratios. The student’s t-test was used between infertile and fertile females to compare BMI. The majority of infertile females were housewives, obese and aged between 36-45 years and consumers of surface water. Moreover, we found the significant positive association of menstrual cramps and the passing of clots during the menstrual cycle, positive family history of infertility and the use of medications to regulate the menstrual periods. On the other hand, the personal history of miscarriages and the use of medications to relieve the menstrual cramps pain showed a non-significant positive association with female infertility. While taking tea or consumption of cold/fizzy drinks was found with a non-significant negative association towards female infertility.

Keywords

Infertility, Housewives, Menstruation Cramps, Obesity, Contraceptives

Reference

[01]	J. Cong, P. Li, L. Zheng, and J. T. Tan, “Prevalence and risk factors of infertility at a rural site of Northern China,” PLoS One, 2016.
[02]	E. Silvestris, G. de Pergola, R. Rosania, and G. Loverro, “Obesity as disruptor of the female fertility,” Reproductive Biology and Endocrinology. 2018.
[03]	A. H. Pakpour, M. S. Yekaninejad, I. M. Zeidi, and A. Burri, “Prevalence and risk factors of the female sexual dysfunction in a sample of infertile Iranian women,” Arch Gynecol Obstet, 2012.
[04]	A. J. Cameron et al., “Clustering of Obesity-Related Risk Behaviors in Children and Their Mothers,” Ann Epidemiol, 2011.
[05]	K. Tremellen, K. Pearce, and D. Zander-Fox, “Increased miscarriage of euploid pregnancies in obese women undergoing cryopreserved embryo transfer,” Reprod Biomed Online, 2017.
[06]	R. J. Hart, “Physiological aspects of female fertility: Role of the environment, modern lifestyle, and genetics,” Physiol Rev, 2016.
[07]	B. Bianco et al., “Polymorphisms of estrogen receptors alpha and beta in idiopathic, infertile Brazilian men: A case-control study,” Mol Reprod Dev, 2011.
[08]	M. Macaluso et al., “A public health focus on infertility prevention, detection, and management,” Fertil Steril, 2010.
[09]	M. N. Mascarenhas, S. R. Flaxman, T. Boerma, S. Vanderpoel, and G. A. Stevens, “National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys,” PLoS Med, 2012.
[10]	A. Direkvand-Moghadam, A. Delpisheh, and A. Khosravi, “Epidemiology of female infertility; a review of literature,” Biosci Biotechnol Res Asia, 2013.
[11]	Q. Meng et al., “Incidence of infertility and risk factors of impaired fecundity among newly married couples in a Chinese population,” Reprod Biomed Online, 2015.
[12]	R. Sharma, K. R. Biedenharn, J. M. Fedor, and A. Agarwal, “Lifestyle factors and reproductive health: Taking control of your fertility,” Reproductive Biology and Endocrinology. 2013.
[13]	D. T. Baird et al., “Fertility and ageing,” Human Reproduction Update. 2005.
[14]	Z. Ö. Dağ and B. Dilbaz, “Impact of obesity on infertility in women,” Journal of the Turkish German Gynecology Association. 2015.
[15]	L. A. Wise, K. J. Rothman, E. M. Mikkelsen, H. T. Sørensen, A. Riis, and E. E. Hatch, “An internet-based prospective study of body size and time-to-pregnancy,” Hum Reprod, 2010.
[16]	J. W. Rich-Edwards et al., “Physical activity, body mass index, and ovulatory disorder infertility,” Epidemiology, 2002.
[17]	B. V. Rossi, M. Abusief, and S. A. Missmer, “Modifiable Risk Factors and Infertility: What Are the Connections?,” Am J Lifestyle Med, 2016.
[18]	Z. Roupa et al., “Causes of infertility in women at reproductive age,” Heal Sci J, 2009.
[19]	S. Shamila and S. Sasikala, “Primary report on the risk factors affecting female infertility in South Indian districts of Tamil Nadu and kerala,” Indian J Community Med, vol. 36, no. 1, pp. 59–61, Jan. 2011.
[20]	L. A. Pratt and D. J. Brody, “Depression and obesity in the U. S. adult household population, 2005-2010,” NCHS Data Brief, 2014.
[21]	B. E. Hamilton, S. J. Ventura, N. E. Skakkebæk, G. Buck Louis, M. O’Bryan, and D. Adamopoulos, “Fertility and abortion rates in the United States, 1960-2002,” in International Journal of Andrology, 2006.