ISSN: 2375-3838
International Journal of Clinical Medicine Research  
Manuscript Information
 
 
Technical Options for Uncrossable Chronic Total Occlusion
International Journal of Clinical Medicine Research
Vol.5 , No. 4, Publication Date: Jun. 7, 2018, Page: 86-89
1405 Views Since June 7, 2018, 619 Downloads Since Jun. 7, 2018
 
 
Authors
 
[1]    

Suryaprakasa Rao Vithala, Apollo Hospital, Hyderguda, Hyderabad, India.

[2]    

Kapardhi Pannala Laxmi Narasimha, Apollo Hospital, Hyderguda, Hyderabad, India.

[3]    

Priyen Kantilal Shah, Apollo Hospital, Hyderguda, Hyderabad, India.

[4]    

Naraynana Rao Ankala Venkata Satya, Apollo Hospital, Hyderguda, Hyderabad, India.

[5]    

Revanur Vishwanath, Apollo Hospital, Hyderguda, Hyderabad, India.

[6]    

Arvind Kumar Srivastava, Apollo Hospital, Hyderguda, Hyderabad, India.

[7]    

Satyajit Mehtre, Apollo Hospital, Hyderguda, Hyderabad, India.

[8]    

Rama Kumari Nuthalapati, Nizam’s Institute of Medical Sciences, Panjagutta, Hyderabad, India.

 
Abstract
 

It has been estimated that chronic total coronary occlusions (CTO) are encountered in 15 to 20% patients referred for CAG. The benefit of CTO revascularization are well established both in terms of improvement in patients’ symptoms as well as improvement in LVEF. We aim in this study to highlight a multitude of techniques that can significantly improve procedural success in this subset of “Uncrossable” CTO lesions. A total number of 436 patients over a period from June 2006 to January 2014 were included. These were patients having either symptomatic angina or documented myocardial ischemia. All patients received loading dose of DAPT Clopidogrel and Aspirin. The lesion was deemed “Uncrossable” if attempts to pass a low profile balloon 1.0 to 1.5 mm were unsuccessful. The failure rate of CTO PCI in our study was 46 cases. In 35 patients coronary guide wire could not able to cross the lesion. The balloon Uncrossable lesions 29 patients. The involved vessels were RCA in 14, LCX in 8 and LAD in 7cases. In 4 patients unable to deploy the stent due to long dissection; small vessels, diffuse disease, unyielding lesions and achieved flow less than TIMI III. We successfully facilitated the balloon and achieved adequate lesion dilatation in 22 patients out of 29 patients. In spite of all these various techniques, in 7 patient lesions were resistant to cross with the balloon. Among seven of these resistant balloon Uncrossable lesion cases, four cases were of LCX lesion, three of RCA lesion and none in case of LAD. The lesion site calcification was invariably present in all patients. The tortuosity at lesion site was noticed in 5, CTO PCI failure were observed in 7 cases. Guide catheters with large size, extra backup, Amplatz and other designed guide catheters provide maximum support. The use of long sheaths, armour guide catheter technique, mother and child technique Guide liner, buddy wire and balloon anchoring including distal anchoring wire technique further provide the strong back up support that is desired when tackling such lesions. In this study we observed Uncrossable lesions in 7.19% cases. The resistant balloon Uncrossable lesions still contributed in 1.59% cases of CTO PCI failure in spite of adaptation of multiple techniques.


Keywords
 

Chronic Coronary Occlusions (CTO), Dual Antiplatelet Drugs (DAPT), Percutaneous Coronary Intervention (PCI)


Reference
 
[01]    

J. Agron Grantham, Stevert Margo, Johnspertus, et al. Chronic total occlusion angioplasty in United States. J Am Coll Cardiol Intv. 2009; 2 (6): 479-486.

[02]    

Pagnotta P, Briguori C, Mango R, et al. Rotational atherectomy in resistant chronic total occlusion. Catheter Cardiovasc Interv. 2010; 76 (3): 366–371.

[03]    

Brilakis ES, Grantham JA, Rinfret S, Wyman RM, Burke MN, Karmpaliotis D, Lembo N, Pershad A, Kandzari DE, Buller CE, DeMartini T, Lombardi WL, Thompson CA. A percutaneous treatment algorithm for crossing coronary chronic total occlusions. JACC Cardiovasc Interv 2012; 5: 367-379.

[04]    

Azzalini L, Vo M, Dens J, Agostoni P. Myths to debunk to improve management, referral, and outcomes in patients with chronic total occlusion of an epicardial coronary artery. Am J Cardiol 2015; 116: 1774-1780.

[05]    

Carlino M, Magri CJ, Uretsky BF, Brilakis ES, Walsh S, Spratt JC, Hanratty C, Grantham JA, Rinfret S, Thompson CA, Lombardi WL, Galassi AR, Sianos G, Latib A, Garbo R, Karmpaliotis D, Kandazari DE, Colombo A. Treatment of the chornic total occlusion: A call to action for the interventional community. Catheter Cardiovasc Interv 2015; 85: 771-778.

[06]    

Kovacic JC, Sharma AB, Roy S et al. Guide liner mother-and-child guide catheter extension: a simple adjunctive tool in PCI for Balloon – Uncrossable chronic total occlusion. J Interv Cardiol 2013 Aug; 26 (4): 343-50.

[07]    

Fujita S, Tamai H, Kyo E, et al. New technique for superior guiding catheter support during advancement of a balloon in coronary angioplasty: The anchor technique. Catheter Cardiovasc Interv. 2003; 59 (4): 482-488.

[08]    

Hirokami M, Saito S, Muto H. Anchoring technique to improve guiding catheter support in coronary angioplasty of chronic total occlusions. Catheter Cardiovasc Interv. 2006; 67 (3): 366-371.

[09]    

Brilkis ES, Banerjee S. Crossing the balloon Uncrossable chronic total occlusion: Tornus to the rescue. Catheter Cardiovasc Interv. 2011; 78 (3): 363-365.

[10]    

Yue Li, Jianqiang Li, Li Sheng, et al. “Seesaw Balloon-Wire Cutting” Technique as a Novel Approach to “Balloon Uncrossable” Chronic Total Occlusions. J Invasive Cardiol 2014; 26 (4): 167-170.

[11]    

Kirtane AJ, Stone GW. The Anchor – Tornus technique: a novel approach to Uncrossable chronic total occlusions. Catheter Cardiovasc Interv. 2007; 70 (4): 554-557.

[12]    

Han Ya –ling, LI Yi, Wang Shou –Li, et al. Multi – wire plaque crushing as a novel technique in treating chronic total occlusions. Chinese medical journal 2008; 121 (6): 518-521.

[13]    

T. Michael, Subhash Banerjee, E. S. Brilakis et al. Subintimal Distal Anchor Technique for “Balloon – Uncrossable chronic total occlusion. J Invasive Cardiol 2013; 25 (10): 552-554.

[14]    

Shen ZJ, Garcia-Garcia HM, Schultz C, et al. crossing of a calcified balloon Uncrossable coronary chronic total occlusion facilitated by a laser catheter: A case report and review recent four years experience at Thorax center. Int J Cardiol. 2010; 145 (2): 251-254.

[15]    

Pagnotta P, Briguori C, Mango R, Visconti G, Focaccio A, Belli G, Presbitero P. Rotational Atherectomy in resistant chronic total occlusions. Catheter Cardiovasc Interv 2010; 76: 366-371.

[16]    

Azzalini L, Dautov R, Ojeda S, Serra A, Benincasa S, Bellini B, Giannini F, Chavarria J, gheorghe LL, Pan M, carlino M, Colombo A, Rinfret S. Long-term outcomes of rotational atherectomy for the percutaneous treatment of chrnoc total occlusions. Catheter Cardiovasc Interv 2016m dio: 10.1002/ccd.26829 [Epub ahead of print].

[17]    

Tomey Mi, Kini AS, Sharma SK. Current status of rotational atherectomy. JACC Cardiovasc. Interv 2014; 7: 345-353.





 
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