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Vol.3 , No. 6, Publication Date: Feb. 8, 2017, Page: 89-94
 thickness changes after Brilliant Blue G (BBG)-assisted internal limiting membrane (ILM) peeling for idiopathic macular hole treatment. Fifteen eyes of fifteen patients who underwent pars plana vitrectomy with ILM peeling were included in the study. Other eyes of the patients were included in the study as control group. BBG assisted ILM peeling performed in 15 eyes. Baseline and, postoperative 3<sup>rd</sup>, 6<sup>th</sup>, and 12<sup>th</sup> months’ BCVA and GCIPL thicknesses were recorded. In the operation group, BCVA improvement (1.06±0.22 to 0.43±0.29 logMar, p=0.0037), inferotemporal and superotemporal GCIPL thickness decrease after surgery (76±2.3 to 65±4.84, p=0.0044, and 73±7.6 to 63±3.82 mµ, p=0.0166, respectively) were statistically significant. In the control group, there was no postoperative statistically significant change. Superotemporal and inferotemporal GCIPL thinning and BCVA improvement in operated eyes showed statistically significant difference comparing to control eyes (p=0.0128, p=0.0024, p=0.0029 respectively). ILM peeling causes retinal morphological changes like irregularities and indentations on the inner surface of the retina, thickening of the nasal retina, temporal GCIPL thinning, and dissociated optic nerve fiber layer during the late postoperative period. GCIPL thinning, particularly in the temporal region, is a common finding after ILM peeling. This may be related to toxic effects of ILM dyes and mechanical trauma.&picture=http://www.aascit.org/aascit/decorators/img/journal/906.jpg)
| [1] | Ibrahim Kocak, Department of Ophthalmology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey. |
| [2] | Haci Koc, Retina Department, Inci Eye Hospital, Sakarya, Turkey. |
| [3] | Hakan Baybora, Department of Ophthalmology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey. |
| [4] | Faruk Kaya, Department of Ophthalmology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey. |
| [5] | Ali Aydin, Department of Ophthalmology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey. |
This article’s aim is to evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL) thickness changes after Brilliant Blue G (BBG)-assisted internal limiting membrane (ILM) peeling for idiopathic macular hole treatment. Fifteen eyes of fifteen patients who underwent pars plana vitrectomy with ILM peeling were included in the study. Other eyes of the patients were included in the study as control group. BBG assisted ILM peeling performed in 15 eyes. Baseline and, postoperative 3rd, 6th, and 12th months’ BCVA and GCIPL thicknesses were recorded. In the operation group, BCVA improvement (1.06±0.22 to 0.43±0.29 logMar, p=0.0037), inferotemporal and superotemporal GCIPL thickness decrease after surgery (76±2.3 to 65±4.84, p=0.0044, and 73±7.6 to 63±3.82 mµ, p=0.0166, respectively) were statistically significant. In the control group, there was no postoperative statistically significant change. Superotemporal and inferotemporal GCIPL thinning and BCVA improvement in operated eyes showed statistically significant difference comparing to control eyes (p=0.0128, p=0.0024, p=0.0029 respectively). ILM peeling causes retinal morphological changes like irregularities and indentations on the inner surface of the retina, thickening of the nasal retina, temporal GCIPL thinning, and dissociated optic nerve fiber layer during the late postoperative period. GCIPL thinning, particularly in the temporal region, is a common finding after ILM peeling. This may be related to toxic effects of ILM dyes and mechanical trauma.
Keywords
Ganglion Cell Inner Plexiform Layer, Internal Limiting Membrane, Macular Hole
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