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Vol.2 , No. 4, Publication Date: Jul. 29, 2015, Page: 39-48
 as an Intervention Impact Assessment in the Management of Hypertension; A Systematic Review&description=Introduction: Persons living with hypertension wrestle with the physical, psychological, and social demands of their illness without adequate help or support from medical care. This has buttressed the need to research into the perceptions of patients in the context of their subjective feelings towards their wellbeing. This is termed “health related quality of life (HRQoL)”. One of the most important goals of all health interventions is to improve the quality of life of persons affected by disease and many researchers had advocated for the need to see health outcome beyond clinical and laboratory parameter alone. Therefore need to study and assess HRQoL as well. This study however set out to review available intervention studies in the scientific literature from 1980 till date (that met the set eligible criteria) and those which employed quality of life as a primary outcome measurement. Methods: The PRISMA and Standard Cochrane Collaboration systematic review techniques were used as guidelines for the review while varieties of online journals, database and library were searched. These yielded over a thousand articles which were screened systematically using stringent eligibility criteria to scale down to 37 articles out of which 6 articles employed intervention as study approach and quality of life as primary outcome measurement. Results: The age range of the participants in the review is between 18 to 80 years. Results revealed that only 4 out of the 6 articles were randomized control trial (RCT) out of which only one was blinded. Four of the studies used SF-36 tool for assessment of HRQoL. Another Four studies reported statistically significant increase in overall HRQoL of intervention group over a control group. Two studies did not analyze significance level. The individual dimensions of HRQoL revealed discrepancies in the reviewed articles. Mental health improvement was observed to be the only common improved outcome across the studies. Conclusion: It was concluded that there is still dearth of literature on HRQoL outcome assessment of hypertensive studies. It is suggested that future research on interventional studies should endeavor to use quality of life as a primary or as part of outcome measurements.&picture=http://www.aascit.org/aascit/decorators/img/journal/906.jpg)
| [1] | Bolarinwa Oladimeji Akeem, Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia (UPM), Selangor, Malaysia; Department of Epidemiology and Community Health, Faculty of Clinical Sciences, University of Ilorin, Ilorin, Nigeria. |
| [2] | Essiet Inimfon Aniema, Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia (UPM), Selangor, Malaysia. |
| [3] | Muhamad Hanafiah Bin Juni, Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia (UPM), Selangor, Malaysia. |
| [4] | Nor Afiah Binti Mohd Zuilkefi, Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia (UPM), Selangor, Malaysia. |
| [5] | Salmiah Binti Md Said, Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia (UPM), Selangor, Malaysia. |
| [6] | Tanimola Makanjuola Akande, Department of Epidemiology and Community Health, Faculty of Clinical Sciences, University of Ilorin, Ilorin, Nigeria. |
Introduction: Persons living with hypertension wrestle with the physical, psychological, and social demands of their illness without adequate help or support from medical care. This has buttressed the need to research into the perceptions of patients in the context of their subjective feelings towards their wellbeing. This is termed “health related quality of life (HRQoL)”. One of the most important goals of all health interventions is to improve the quality of life of persons affected by disease and many researchers had advocated for the need to see health outcome beyond clinical and laboratory parameter alone. Therefore need to study and assess HRQoL as well. This study however set out to review available intervention studies in the scientific literature from 1980 till date (that met the set eligible criteria) and those which employed quality of life as a primary outcome measurement. Methods: The PRISMA and Standard Cochrane Collaboration systematic review techniques were used as guidelines for the review while varieties of online journals, database and library were searched. These yielded over a thousand articles which were screened systematically using stringent eligibility criteria to scale down to 37 articles out of which 6 articles employed intervention as study approach and quality of life as primary outcome measurement. Results: The age range of the participants in the review is between 18 to 80 years. Results revealed that only 4 out of the 6 articles were randomized control trial (RCT) out of which only one was blinded. Four of the studies used SF-36 tool for assessment of HRQoL. Another Four studies reported statistically significant increase in overall HRQoL of intervention group over a control group. Two studies did not analyze significance level. The individual dimensions of HRQoL revealed discrepancies in the reviewed articles. Mental health improvement was observed to be the only common improved outcome across the studies. Conclusion: It was concluded that there is still dearth of literature on HRQoL outcome assessment of hypertensive studies. It is suggested that future research on interventional studies should endeavor to use quality of life as a primary or as part of outcome measurements.
Keywords
Hypertension, Intervention, Health Related Quality of Life
Reference
| [01] | Abdel-Hameed I.M. .Ebid, Zina T. Ali, Mohamed A.F. Ghobary (2004). Blood pressure control in hypertensive patients: impact of anEgyptian pharmaceutical care model. J App Pharm Sci, 2014; 4(09): 093-101 |
| [02] | Aghajani M, Ajorpaz NM, Atrian MK, Raofi Z, Abedi F, Vartoni SN et al. (2013). Effect of self-care education on quality of life in patients with primary hypertension: Comparing lecture and educational packages. Nurs Midwifery stud. 2 (4): 71 – 6. |
| [03] | Anderson, C., Rubenach, S., Ni Mhurchu, C., Clark, M., Spencer, C., Winsor, A. (2000). Home or Hospital for Stroke Rehabilitation? Results of a Randomized Controlled Trial I: Health Outcomes at 6 Months. Stroke. 31: 1024-103 |
| [04] | Bernocchi, P., Scalvini, S., Bertacchini, F., Rivadossi, F., Muiesan, M.L. (2014). Home based telemedicine intervention for patients with uncontrolled hypertension for patients with uncontrolled hypertension:- a real life non-randomized study. BMC medical informatics and decision making. 14 : 52. |
| [05] | Biradar S.S, Kapatae R, Reddy S, Raju SA. (2012).Assessment of pharmacist mediated patient counselling on hypertensiveincompliance with quality of life in south Indian city. International research journal of pharmacy; 206-209. |
| [06] | Brotons, C., Falces, C., Alegre, J., Ballarín, E., Casanovas, J., Catà, T., Martínez, M., et al. (2009). Randomized Clinical Trial of the Effectiveness of a Home-Based Intervention in Patients With Heart Failure: The IC-DOM Study. Rev EspCardiol. 62(4):400-8. |
| [07] | Chobanian, A.V., Bakris, J.L., Black, H.R., Cushman, W.C., Green, L.A., Izzo, J.L., et al. (2003). Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report. The Journal of the American Medical Association. 289(9): 2560. |
| [08] | CONSORT group (2010). Available at http://www.consort-statement.org/checklists/view/32-consort/66-title accessed on 20/03/15. |
| [09] | Cote I, Moisan J, Chabot I, Gregiore JP (2005). Health related quality of life in hypertension: Impact of a pharmacy intervention programme. J Clin Pharm Ther. 30 (4): 355 - 62 |
| [10] | Dalal, H.M., Evans, P.H., Campbell, J.L., Taylor, R.S., Watt, A., Read, K.L.., et all (2007). Home-based versus hospital-based rehabilitation after myocardial infarction: A randomized trial with preference arms--Cornwall Heart Attack Rehabilitation Management Study (CHARMS).Int J Cardiol.;119(2):202-11. |
| [11] | Elshamy K, Elasafety E (2011). Effect of nursing intervention using foot refloxology on blood pressure and quality of life of hypertensive patients at Mansoura University Hospital: Preliminary Result. Med. J. Cairo Univ.: 79 (2): 193 – 202. |
| [12] | Ferrans CE, Zerwic JJ, Wilbur JE and Larson JL (2005): Conceptual model of health-related quality of life. J NursScholarsh. 37(4):336-342. |
| [13] | FedermanA.D., and Soriano T. (2014). More Promise for Home-Based Primary Care. JAMA Intern Med. doi:10.1001/jamainternmed.2014.3399 |
| [14] | Higgins JPT, Green S, eds. Cochrane Handbook for SystematicReviews of Interventions Version 5.1.0 [updated March 2011].The Cochrane Collaboration, 2011. www.cochrane-handbook.org |
| [15] | Ike, S.O., and Onwubere, B.J. (2003). The relationship between diastolic dysfunction and level of blood pressure in Blacks. Ethnicity & disease, 13(4), 463-469. |
| [16] | Inglis S.C., Pearson S., Treen S., Gallasch T., Horowitz J.D., and Stewart S. (2006). Extending the horizon in chronic heart failure: effects of multidisciplinary, home-based intervention relative to usual care. Circulation. 5;114(23):2466-73 |
| [17] | IssaBA., and Baiyewu O. (2006). Quality of life of patients with Diabetes Mellitus in a Nigerian Teaching Hospital. Hong kong J Psychiatry. 16: 27-33. |
| [18] | James, P.A., Oparil, S., Carter, B.L., Cushman, W.C., Dennison-Himmelfarb, C., Hadler, J., et al (2014). 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults Report From the Panel Members Appointed to the 8th Joint National Committee (JNC 8). JAMA. 2014;311(5):507-520.doi:10.1001/jama.2013.284427. |
| [19] | JekelJF, Elmore JG, Katz DL. Epidemiology, Biostatistics and Preventive Medicine. 3rdedition. Saunders. 2008 |
| [20] | Jolly, K., Lip, G.Y., Taylor, R.S., Raftery, J., Mant, J., Lane, D., et al. The Birmingham Rehabilitation Uptake Maximisation study (BRUM): A randomised controlled trial comparing home-based with centre-based cardiac rehabilitation.Heart. 2009 Jan;95(1):36-42. doi: 10.1136/hrt.2007.127209. |
| [21] | Kring DL. (2008). Using the Revised Wilson and Cleary Model to Explore Factors Affecting Quality of Life in Persons on Hemodialysis. Dissertation submitted to the Faculty of The Graduate School at the University of North Carolina. Available at: http://libres.uncg.edu/ir/uncg/f/umi-uncg-1532.pdf. accessed on 24/02/15. |
| [22] | Leal J, Luengo-Fernandez R, Gray A, Petersen S, Rayner M: Economic burden of cardiovascular diseases in the enlarged European Union. Eur Heart J 2006, 27:1610-1619. |
| [23] | Lewington, S., Clarke, R., Qizilbash, N., et al. (2002). Prospective Studies Collaboration: Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 360 (9349):1903-1913 |
| [24] | Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009;6:e1000097 |
| [25] | Nelissen H.E., and Hendriks M.E,. WIT Ferdinand W.N.M.,Bolarinwa O.A., Osagbemi G.K., Bindraban N.R. et al (2014). Target Organ Damage among Hypertensive adults in Rural Nigeria: A cross sectional study. Journal of Hypertensive. 32 (3):487-494 |
| [26] | Odili, V.U., Ugboka, L.U., &Oparah, A.C. (2010). Quality Of Life Of People With Diabetes In Benin City As Measured With WHOQOL- BREF. The Internet Journal of Law, Healthcare and Ethics. 6(2) |
| [27] | OgedegbeG,Gyamfi, J, Plange-Rhule, J, SurkisA,Rosenthal DM, Airhihenbuwa C., et al. (2004). Task shifting interventions forcardiovascular risk reductionin low-income and middle-incomeountries: a systematic reviewofrandomised controlled trials. BMJ Open 2014;4:e005983. doi:10.1136/bmjopen-2014-005983 |
| [28] | Ogunlana M.O., Adedokun B., Dairo M.D., and Odunaiya N.A. (2009). Profile and predictor of health-related quality of life among hypertensive patient in south-western Nigeria. BMC Cardiovascular Disorders. 9: 25. |
| [29] | Opadijo, O.G., Omotoso, A.B.O., Akande, A.A. (2003). Relation of electrocardiographic left ventricular hyper-trophy to blood pressure, body mass index, serum lipids and blood sugar levels in adult Nigerians. African Journal of Medicine and Medical Sciences.2003;32 (4), 395-399. |
| [30] | Pezzin, L.E., Feldman, P.H., Mongoven, J.M., McDonald, M.V., Gerber, L.M., Peng, T.R. (2010). Improving Blood Pressure Control: Results of Home-based Post-acute Care Interventions. J Gen Intern Med 26(3):280–6 |
| [31] | RAND Health. Medical Outcome Study (MOS). Available at; http://www.rand.org/health/surveys_tools/mos/mos_core_36item_terms.html.Accessed 24/02/2014 |
| [32] | Rubin, R.R., Peyrot, M. (1999). Quality of life and diabetes. Diabetes Metab Res Rev; 15(3): 205-218. |
| [33] | Saleem, F., Hassali, M. A., Shafie, A. A., UlHaq, N., Farooqui, M., Aljadhay, H. and Ahmad, F. U. D. (2013), Pharmacist intervention in improving hypertension-related knowledge, treatment medication adherence and health-related quality of life: a non-clinical randomized controlled trial. Health Expectations. doi: 10.1111/hex.12101 |
| [34] | Sinclair, A.J., Conroy, S.P., Davies, M., Bayer, A.J. Post-discharge home-based support for older cardiac patients: a randomised controlled trial.Age and Ageing 2005; 34: 338–343.doi:10.1093/ageing/afi116 |
| [35] | Staessen, J.A.,, Den Hond, E., Celis, H., Fagard, R., Keary, L., Vandenhoven, G., O'Brien. E.T. (2004). Antihypertensive treatment based on blood pressure measurement at home or in the physician's office: a randomized controlled trial. JAMA. 291: 955–64 |
| [36] | Stewart S., Marley J.E., and Horowitz J.D. (1999). Effects of a multidisciplinary, home-based intervention on planned readmissions and survival among patients with chronic congestive heart failure: a randomised controlled study Lancet. 354 : 1077 – 83 |
| [37] | Wagner E.H., Austin B.T., Davis C., Hindmarsh M., Schaefer J., and Bonomi A. (2001). Improving Chronic Illness Care: Translating Evidence IntoAction.Health Affairs. 20 (6): 64 – 78 |
| [38] | Wal P, Wal A, Bhandari A, PandeyU,Rai AK (2013). Pharmacist involvement in the patient care improvesoutcome in hypertension patients. J Res Pharm Pract;2:123-9. |
| [39] | Wandell, P.E. (2005). Quality of life of patients with diabetes mellitus. An overview of research in primary health care in the Nordic countries. Scand J Prim Health Care. 23(2):68-74. |
| [40] | Wang,W., Chair, S.Y., Thompson, D.R., Twinn, S.F. (2012). Effects of home-based rehabilitation on health-related quality of life and psychological status in Chinese patients recovering from acute myocardial infarction. Heart & Lung. 4 (1): 15 -25. |
| [41] | Wilson, I.B., & Cleary, P.D. (1995). Linking clinical variables with health-related quality of life: A conceptual model of patient outcomes. JAMA, 273(1), 59-65. |
| [42] | Wolff M, Sundquist K, Loon SL, Midlov P (2013). Impact of yoga on blood pressure andquality of life in patients with hypertension – a controlled trial inprimary care, matched for systolic blood pressure. BMC Cardiovascular Disorders: 13:111. |
| [43] | WHO (1948). Available at http://www.who.int/about/definition/en/print.html. Accessesd on 24/02/15 |
| [44] | WHOQOL GROUP. (1998). The World Health Organization quality of life assessment (WHOQOL): Development and general psychometric properties. Soc. Sci Med. 46: 1569-83. |
| [45] | Yu HU, Junven ZHU (1999). Quality of life of patients with mild hypertension treated with Captopril: a randomized double blind placebo controlled clinical trial. Chin Med J: 112 (4): 3022307 |
