Vol.2 , No. 6, Publication Date: Oct. 28, 2015, Page: 71-75
[1] | Toshiaki Funada, Department of Material Science and Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Showa-ku, Nagoya, Japan. |
[2] | Tetsuo Ohkuwa, Department of Material Science and Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Showa-ku, Nagoya, Japan. |
[3] | Katsumi Hirai, New Health Foods Corp., Yaizu, Shizuoka, Japan. |
[4] | Hiroshi Itoh, Department of Material Science and Engineering, Graduate School of Engineering, Nagoya Institute of Technology, Showa-ku, Nagoya, Japan. |
[5] | Takao Tsuda, Pico-device Co., Ltd., Incubation Center, Chikusa-ku, Nagoya Japan. |
This study investigated the volatile organic compounds (VOCs) in human skin gas and standard gas using modified gas chromatographic system. It devised sampling glass syringe temperature at 25°C or heating 80°C prior to injecting sampling gas into a gas chromatograph. The peak area of 6-methyl-5-hepten-2-one at 50, 100, and 250 ppb heated at 80°C was 337, 236, and 214% higher than that at 25°C, respectively. The peak area of hexanal at 50, 100, and 250 ppb heated at 80°C was 164, 159, and 135% higher than that heated at 25°C, respectively. Likewise, the peak area of acetone at 50, 100, and 250 ppb heated at 80°C was 115, 116, and 109% higher than that heated at 25°C, respectively. These results suggest that a higher VOC peak area can be obtained by heating the sampling glass syringe before injection into the gas chromatograph.
Keywords
Volatile Organic Compounds, Human Skin Gas, 6-Methyl-5-hepten-2-one, Hexanal, Acetone
Reference
[01] | W. Filipiak, V. Ruzsanyi, P. Mochalski, A. Filipiak, A. Bajtarevie, C. Ager, W. Denz, W. Hilbe, H. Jamnig, M. Hackl, A. Dzien and A. Amann; J. Breath. Res., 2012; 6, 036008. |
[02] | K. Nose, T.Mizuno, N. Yamane, T. Kondo, H. Ohtani, S. Araki, T.Tsuda; Anal. Sci. 2005; 21, 1471. |
[03] | N. Yamane, T. Tsuda, K. Nose, A. Yamamoto, H. Ishiguro, T. Kondo; Clin. Chim. Acta. 2006; 365, 325. |
[04] | P. Mochalski, J. King, K. Unterkofler, H. Hinterhuber and A. Amann; J. Chromatogr. B, 2014; 959, 62. |
[05] | M. Righettoni, A. A. Schmid, A. Smann and S. E. Pratsinis; J. Breath. Res., 2013; 7, 037110. |
[06] | C. Turner, B. Parekh, C. Walton, P. Spanel, D. Smith and M. Evans; Rapid Commun. Mass Spectrom., 2008; 22, 526. |
[07] | C. Turner, C. Walton, S. Hoashi, and M. Evans; J. Breath. Res., 2009; 3, 0460004. |
[08] | K. Yamai, T. Funada, T. Ohkuwa, H. Itoh, T. Tsuda; Anal. Sci. 2012;28, 511 |
[09] | P. Mochalski, K. Unterkofler, H. Hinterhuber and A. Amann; Anal. Chem., 2014; 86, 3915. |
[10] | P. Fruekilde, J. Hjorth, N. R. Jensen, D. Kotzias and B. Larsen; Atmospheric Environment, 1998; 32, 1893. |
[11] | A. Wisthaler and C. J. Weschler; PNAS, 2010; 13, 6568. |
[12] | L. Petrick and Y. Dubowski; Indor Air, 2009; 19, 381. |
[13] | S. Haze, Y. Gozu, S. Nakamura, Y. Kohno, K. Sawano, H. Ohta and K. Yamazaki; J. Invest. Dermatol, 2001; 116, 520. |
[14] | K. Mori, T. Funada, M. Kikuchi, T. Ohkuwa, H. Itoh, Y. Yamazaki, and T. Tsuda; Redox Rep., 2008; 13, 139. |
[15] | K. Naito, Y. Inai and T. Hirabayashi; Anal. Chem., 2000; 72, 2797. |
[16] | J. C. Sternberg, W. E. Gallaway, D. T. L. Jones, N. Brenner J. E. Callen, and M. D. Weiss;“Gas Chromatography”, 1962; Academic Press, New York, 231. |
[17] | T. Tsuda;“Chromatography (in Japanese)”, 1995; Maruzen, Tokyo, 81. |