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International Journal of Chemical and Biomedical Science

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The Influence of Gliatilin on Excitability of Spinal Motorneurons After Spinal Cord Contusion

International Journal of Chemical and Biomedical Science
Vol.1 , No. 3, Publication Date: Jul. 22, 2015, Page: 79-82

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Authors

[1]	Guzel G. Iafarova, Institute of Basic Medicine and Biology, Kazan Federal University, Kazan, Russia; Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan, Kazan, Russia.
[2]	Elgizar К. Valeev, Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan, Kazan, Russia.
[3]	Rustem F. Tumakaev, Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan, Kazan, Russia.
[4]	Igor A. Lavrov, Institute of Basic Medicine and Biology, Kazan Federal University, Kazan, Russia.
[5]	Tatyana V. Baltina, Institute of Basic Medicine and Biology, Kazan Federal University, Kazan, Russia.

Abstract

In this study we evaluated the influence of gliatilin on the level of excitability of spinal motorneurons and on the functional state of peripheral part of the neuromotor system after spinal cord contusion. Two periods of a traumatic illness were evaluated with electromyography on dog's model. Compare with control animals, in group that received gliatilin we observed a stable level of excitability of spinal motorneurons and functioning of peripheral part of the neuromotor system. It is suggested that gliatilin, being a donor of a glitcerophosphat, could maintain the integrity of neural cells membranes by restoration of the synthesis of phospholipids and carries out a neuroprotective effect.

Keywords

Spinal Cord Contusion, Electroneuromyography, Gliatilin, Motorneurons Excitability

Reference

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