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AASCIT Communications | Volume 3, Issue 3 | Mar. 28, 2016 online | Page:132-138
Antimicrobial Activity of Ceftazidime (CFZ) Complexes with Two Different Nanosized Metal Salts
The antimicrobial activity of Ceftazidime (CFZ) complexes was studied with nanosized cadmium chloride and nano copper sulphate salts. Firstly, preparation of the nanosized metal complexes with Ceftazidime antibiotic (CFZ) using ball milling method then, characterization were done using transmission electron microscope. Finally, the antimicrobial activity was estimated based on size of inhibition zone formed around discs of the used CFZ antibiotic and its nanosized metal-complexes on a petri dish with Luria Bertani agar (LB-agar) plates to conclude that nanosized-CdCl2 complex has higher antimicrobial activity and act as more potent bacteriostatic agents to inhibiting the growth of the microorganisms.
E. A. Gomaa, Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
S. E. Salem, Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Ceftazidime Antibiotic (CFZ), Ball Milling Method, Transmission Electron Microscopy (tem), Inhibition Zone, Antimicrobial Activity
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Abou Elleef, Elsayed M., Gomaa Esam A., Shereen E Salem, Thermodynamic effect of bulk and nano-CuSO4 salts on ceftazidime antibiotic using variety of differet techniques, American Journal of Chemistry and Application, 2, 1(2015)1-11.
Gomaa Esam A., Ibrahim Kamal M., Zaky Rania R., Ibrahim Amr A, Hassan Nermeen M., Thermodynamic interaction parameters for bulk and nano Cobalt sulfate (CS) with LHC in ternary 5%DMSO (EtOH-H2O(70-30)) mixture at different temperatures, AASCIT Journal of Chemistry, 2, 2(2015)7-18.
Gomaa Esam A, Zaky Rania R., Fekri Ahmed, Abdel –Fattah Mohamed A, Thermodynamics of solvation for nano and bulk lead bromide in mixed DMF-H2O solvents at different temperatures, American Journal of Materials Research 2(1), (2015) 16-21.
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Arcticle History
Submitted: Mar. 6, 2016
Accepted: Mar. 14, 2016
Published: Mar. 28, 2016
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