The importance of zinc oxide (ZnO) in the human body was studied of electrochemical properties through its effect on human blood medium as oxidative or antioxidant reagent using cyclic voltammetric(CV) technique by glassy carbon electrode (GCE). The results found the oxidation-reduction current peaks of zinc oxide appeared in the blood medium at -1 and -1.35 V respectively. The effect of ascorbic acid and folic acid on the zinc oxide was studied in blood medium. It was found that the oxidation current peak of ascorbic acid (AA) acts for reducing the oxidation current peak of zinc oxide and absent the reduction current peak. While Folic acid (FA) was affected on the both oxidation – reduction current peaks of zinc oxide in blood medium by enhancement the cathodiccurrent peak and reducing the anodic current peak. So, folic acid acts as a good antioxidant agent using with zinc ions in human body.
Muhammed Mizher Radhi, Wee Tee Tan, Mohamad Zaki B. Ab Rahman and Anuar Bin Kassim, Voltammetric Detection of Mn(II) in Blood Sample at C60 and MWCNT Modified Glassy Carbon Electrodes. American Journal of Applied Sciences 7 (3): 439-445, 2010.
Muhammed M. Radhi, Dawood S. Dawood, Nawfal K. Al-Damlooji and Tan W. Tee, Development of Electrochemical Sensors for the Detectionof Mercury by CNT/Li+, C60/Li+ and Activated Carbon Modified Glassy Carbon Electrode in Blood MediumSensors & Transducers Journal, Vol. 146, Issue 11, November 2012, pp. 191-202.
Muhammed Mizher Radhi, Nawfal Khalid Al-Damlooji, Baquir Kareem Abed, Dawood Salman Dawood, and Tan Wee Tee, Electrochemical Sensors for Detecting Mn (II (in Blood Medium Sensors & Transducers, Vol. 149, Issue 2, February 2013, pp. 89-93.
Muhammed Mizher Radhi, Nawfal K. Al-Damlooj, Mahmood Radhi Jobayr, Dawood S. Dawood, Electrochemical Sensors of Cyclic Voltammetry to Detect Cd(II) in Blood Medium Sensors & Transducers, Vol. 155, Issue 8, August 2013, pp. 150-154.
Benjamin J. Feldman, Alessandra D’Alessandro, John D. Osterloh, and Bernard H. Hata, Electrochemical Determination of Low Blood Lead Concentrations with a Disposable Carbon Microarray Electrode, Clin. Chem. Monitoring and Toxicology, 41(4), 557-563 (1995).
Paul A. Kilmartin, Electrochemical Detection of Natural Antioxidants:Principles and Protocols, antioxidants & redox signaling, Volume 3, Number 6, 2001
N. Ossendorfova, J. Pradac, J. Paradacova, J. Koryta, Cyclic voltammetric response of blood serum, Journal of Electroanalytical Chemistry and Interfacial Electrochemistry Vol. 58, Issue 1, 1975, PP. 255-261.
Lucia H. Mascaroa, M. C. Santosb, S. A. S. Machadob and L. A. Avaca, Voltammetric and Rotating Ring-Disk Studies of the Influence of Anions in the Underpotential Deposition of Zinc on Platinum, J. Braz. Chem. Soc., Vol. 13, No. 4, 529-534, 2002.
Preetha Jothimuthu, a Robert A. Wilson, b Josi Herren, a Xing Pei, a Wenjing Kang, a Rodney Daniels, c Hector Wong, c Fred Beyette, a William R. Heineman, b and Ian Papautsky, Zinc Detection in Serum by Anodic Stripping Voltammetry on Microfabricated Bismuth Electrodes, Electroanalysis. 2013 Feb; 25(2): 10.1002/elan.201200530.
Jiri Sochor, Jiri Dobes, Olga Krystofova, Branislav Ruttkay-Nedecky, Petr Babula, Miroslav Pohanka, Tunde Jurikova, Ondrej Zitka, Vojtech Adam, Borivoj Klejdus, Rene Kizek, Electrochemistry as a Tool for Studying Antioxidant Properties, Int. J. Electrochem. Sci., 8 (2013) 8464–8489.
Shinde Brijalal Ramdas, Ascorbic Effect on the endosulphan induced alterations in Blood Glucose level of the Freshwater Fish, Central European Journal of Experimental Biology, 2013, 2 (3):1-3.
Sukhavasi S, Jothimuthu P, Papautsky I, Beyette FR Jr., Development of a Point-of-Care device to quantify serum zinc to aid the diagnosis and follow-up of pediatric septic shock., ConfProc IEEE Eng Med Biol Soc. 2011;2011:3676-9.
Muhammed Mizher Radhi, Hanaa Naji Abdullah, Sura A. Al-Asadi, Emad A. Jaffar Al-Mulla, Electrochemical oxidation effect of ascorbic acid on mercury ions in blood sample using cyclic voltammetry, Int J IndChem, 6(4), 311-316, 2015
Yavuz Yardim, Ziihre Entürk, Electrochemical Behavior of Folic Acid at A Boron-Doped Diamond Electrode: Its Adsorptive Stripping Voltammetric Determination in Tablets, Turk J Pharm Sci 11(1), 87-100, 2014.