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AASCIT Communications | Volume 2, Issue 6 | Nov. 27, 2015 online | Page:293-295
Young vs Old Patients: Nosocomial Infections and Fungal Biofilms Severity
In the hospital, the care of patients changes with several parameters (immunosuppression, antibiotics, invasive procedure ...). However, are nosocomial infections and fungal biofilms severity varying between young and old patients? is that true for the different age bracket? According to many researches, the extreme age (lower than one year and over 65) exposes more patients to the risk of nosocomial infections. Our study showed that there is no difference between these infections and fungal biofilms formation on the surfaces of implanted catheters to both categories of patients, young and old.
S. M. L. Seddiki, University Center of Naâma, Institute of Sciences, Dept. of nature and life sciences, Naâma, Algeria; Laboratory Antifungal Antibiotic, Physico-chemical synthesis and biological activity, University of Tlemcen, Imama, Algeria.
Z. Boucherit-Otmani, Laboratory Antifungal Antibiotic, Physico-chemical synthesis and biological activity, University of Tlemcen, Imama, Algeria.
D. Kunkel, Dennis Kunkel Microscopy Inc, Kailua, USA.
Nosocomial Infections, Age, Gender, Fungal Biofilms, Scanning Electron Microscopy
Seddiki S.M.L., Boucherit-Otmani Z., Bettioui R.A., Boucherit K., Taleb M. and Kunkel D. (2015) Nosocomial Fungal Infectivities: In Vivo Formation of Candida Biofilms on Catheters Surfaces. American Journal of Microbiology and Biotechnology; 2: 38-43.
Rebiahi S.-A., Rahmoun M., Seddiki S.M.L., Kadi K., Belhadji F., Chabni N., Kunkel D. (2014) Nosocomial infections caused by Staphylococcus aureus biofilm producer in the neonatal unit of the hospital specialist mother-child of Tlemcen, Algeria. Journal de pédiatrie et de puériculture; 27: 228-235.
Chandra J., Mukherjee P.K., Ghannoum M.A. (2008) In vitro growth and analysis of Candida biofilms. Nat Protoc; 3: 1909-1924.
Fox E.P., Bui C.K., Nett J.E., Hartooni N., Mui M.C., Andes D.R., Nobile C.J. and Johnson A. D. (2015) An expanded regulatory network temporally controls Candida albicans biofilm formation. Molecular Microbiology; 96: 1226-1239.
Douglas L.J. (2003) Candida biofilms and their role in infection. Trends Microbiol; 11: 30-36.
Karlović Z., Perić M., Vladić D., Kosjerina A. and Majerić-Kogler V. (2013) The significance of demographic factors (age, sex, preoperative physiological status) and type of surgery on patients’ outcome in ICU. Signa Vitae; 8: 42 - 48.
Stéphan F., Cheffi A. and Bonnet F. (2001) Nosocomial infections and outcome of critically ill elderly patients after surgery.; Anesthesiology; 94: 407-14.
Develoux M. and Bretagne S. (2005) Candidoses et levuroses diverses. EMC-Maladies Infectieuses; 2: 119 - 139.
Gavazzi G., Mallaret M.R., Couturier P., Iffenecker A. and Franco A. (2002) Bloodstream infection: differences between young-old, old, and old-old patients. J Am Geriatr Soc; 50: 1667-1673.
Bochicchio G.V., Joshi M., Knorr K.M. and Scalea T.M. (2001) Impact of nosocomial infections in trauma: does age make a difference? J Trauma; 50: 612-7; discussion 617-9.
Chow J.K., Golan Y., Ruthazer R., Karchmer A.W., Carmeli Y., Lichtenberg D., Chawla V., Young J. and Hadley S. (2008) Factors Associated with Candidemia Caused by Non-albicans Candida Species versus Candida albicans in the Intensive Care Unit. Clinical Infectious Diseases; 46: 1206- 1213.
Paulitsch A. H., Willinger B., Zsalatz B., Stabentheiner E., Marth E. and Buzina W. (2009) In-vivo Candida biofilms in scanning electron microscopy. Medical Mycology; 47: 690–696.
Arcticle History
Submitted: Apr. 3, 2015
Accepted: Oct. 7, 2015
Published: Nov. 27, 2015
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